IN THE NOW AND IN THE KNOW
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LONGVIDA & IMPACT TO JOINT INFLAMMATION

AUGUST 2019 – Equine osteoarthritis (OA), or the breakdown of joint cartilage and underlying bone due to inflammation, is extremely common in horses across a wide spectrum of age and activity level.1 Joint inflammation is often naturally occurring and may result from a myriad of factors, including infection, age, and years of joint use.1 Despite decades of research, a reversal of the OA disease process remains evasive.2 Because horses suffering from joint inflammation can experience pain, stiffness, and lameness, pain control is key in keeping arthritic horses comfortable.1 

The results of a two-period crossover study performed at Louisiana State University School of Veterinary Medicine and presented at the American Association of Equine Practitioners (AAEP), suggests that Longvida® may help to reduce pain and alleviate lameness in horses with OA.3 The study sought to evaluate the effects of an oral herbal supplement containing Longvida® Optimized Curcumin on lameness and joint pain in horses with OA.3 A gastroscopy observation was also performed to observe the supplement’s effects on stomach health.3 

The study evaluated six thoroughbred horses with naturally occurring OA.3 Test subjects either received grain (control) or grain top-dressed with the herbal supplement once per day for thirty days.3 Researchers collected lameness data on Day 0, Day 15, and Day 30 of the study, blood sample data on Day 1 and Day 14, and gastroscopy data on Day 0 and Day 31.3

The study concluded that the herbal supplement was safe when fed to horses, reducing pain on palpation and improving weight-bearing in lame legs after 30 days of feeding in Longvida® treated horses.3 No adverse responses were noted in the treated horses. Stomach health was also maintained throughout the treatment process.3

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Despite the wide array of joint supplements available for horses, the majority of these products have been shown by independent laboratory analyses to contain less of their active ingredients than their labels suggest, creating what some call a “buyer-beware market” in which veterinarians and horse owners alike must rely on limited research and company reputations when selecting a supplement . For this reason, Longvida® stands out as an optimal alternative for owners seeking a reliable, research-backed alternative to improve their horses’ mobility and quality of life.3, 4 

“As we celebrate 10 years of having Longvida® available on the market, our team at Verdure continues to be excited by the powerful ingredient’s seemingly limitless frontier of health applications. The results of this equine study yet again demonstrate Longvida’s robust potential for supporting healthy aging in animals as well as people, and if history is any indication, we anticipate that future studies will not only provide further substantiation of these benefits but also inspire research into new areas of potential application. Longvida® is show-safe, making it a viable option for a greater number of horses, including those that train often and might very well benefit most from the supplement. Longvida® is backed by the non-GMO Project Verified certification, glyphosate residue free certification, sports banned substances testing, NASC (National Animal Supplement Council) preferred ingredient status, roughly 30 clinical trials, and so much more. The past decade of mounting research and support for Longvida® truly sets the standard for high-caliber ingredients,” said Kristen Marshall, Marketing Coordinator at Verdure Sciences.

 

About Verdure Sciences®:  Verdure Sciences manages ingredient innovation throughout the integration of supply network, production, and research platforms. With an expanding pipeline of proprietary, standardized botanical ingredients supported by pharmacokinetic, pharmacodynamic, and clinical research profiles, we work toward our unified vision to offer safe, effective ingredient solutions. Verdure Sciences® is a registered trademark of Verdure Sciences®, Inc.

For our most current patent and trademark information, please visit: www.vs-corp.com/ip   | Visit www.vs-corp.com for more information.

About Longvida®:  Longvida® Optimized Curcumin is a breakthrough formula of the natural antioxidant curcumin, from the turmeric root, optimized to deliver free curcumin. It was designed by university neuroscientists using a patented Solid Lipid Curcumin Particle (SLCP™) Technology that promotes the uptake of free curcumin to the blood and target tissues. Exclusively licensed to Verdure Sciences, Longvida® is able to bypass initial hydrolysis and deliver bioefficacious levels of unglucuronidated (free) curcumin to the brain and target tissues. Longvida® has been extensively studied by independent researchers globally and offers efficacious amounts of free curcumin at easily managed daily doses.

For our most current patent and trademark information, please visit: www.vs-corp.com/ip

For a list of current Longvida references, please visit: http://marketing.vs-corp.com/longvida-science

 

References:

  1. What You Need to Know About Equine Osteoarthritis. (2018, December 27). Retrieved from https://thehorse.com/164328/what-you-need-to-know-about-equine-osteoarthritis/
  2. Kentucky Equine Research Staff. “Cure for Equine Osteoarthritis Eludes Researchers.” Kentucky Equine Research, 13 Feb. 2018, ker.com/equinews/cure-equine-osteoarthritis-eludes-researchers/.
  3. Andrews FM et al. Effect of Absorbine Bute-Less Performance supplement containing curcumin extract (Longvida® SD Optimized Curcumin) in horses with osteoarthritis or degenerative joint disease. Presented at American Association of Equine Practitioners (AAEP). 2017 Dec. Retrieved July 2019 from https://absorbine.com/clinical-research/bute-less-performance-supplement/
  4. Liu Y et al. Simultaneous quantification of free curcuminoids and their metabolites in equine plasma by LC-ESI-MS/MS. J Pharma Biomed Analysis. 2018 May 30. Volume 154: 31-39. doi: 10.1016/j.jpba.2018.03.014
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Please note that the physiological activity of the ingredient(s) described herein is supported by the referenced clinical trial reports. Marketers of finished products containing the ingredient(s) described herein are responsible for determining whether claims made for such products are lawful and in compliance with the laws of the country in which they will market the products.
For our most current patent information, please visit: www.vs-corp.com/ip