AUGUST 2021 – A recently published study with Bacognize®, a proprietary Bacopa monnieri extract, reported numerous findings in emotional and mental wellbeing, alertness, focus, impact on sleep, stress, and other quality of life markers.
The ability of Bacognize® to help with alertness and focus has been seen in previous clinicals, including when subjects were under stressful test taking circumstances (Kumar et al, 2016). Previous studies also have looked at the mechanistic abilities of Bacognize® to interact on HT1a receptors associated with serotonin uptake. With this knowledge, researchers examined the ability of Bacognize® to act as an adaptogen, modulating the serotonin / melatonin pathways associated with alertness, focus, and a healthy circadian rhythm.
Recently, researchers examined administration of 150mg Bacognize® (twice daily) and its impact on quality of life (QOL) measures, including emotional wellbeing, alertness, and quality of sleep. Eighty-nine healthy men and women aged 18-70 years with self-reported sleep problems showed positive improvements in salivary biomarkers measures with Bacognize® when compared to placebo in all QOL measures (alertness upon awakening, emotional wellbeing, general health, and pain), with positive changes in PM melatonin, decreases in CRP, and trending increase of morning cortisol levels. The ability to improve grogginess was significant. No adverse effects were observed in the Bacognize® group attributed to supplementation.
“Conducting a human clinical during the COVID-19 pandemic did present some unusual challenges; however, the results are encouraging. Stress and quality of life have definitely been brought to the forefront during these times, with an ever-broadening appreciation of adapting capabilities. This study suggests that Bacgonize® extract indeed has the ability to help individuals respond and adapt without any negative impacts to the sleep cycle, with specific support in mood, emotional wellbeing, focus, attention, and overall cognitive vitality,” explained Sonya Cropper, VP of marketing and innovation at Verdure Sciences.
Researchers stated that Bacognize® supplementation (300mg/day) was associated with statistically significant improvements to emotional wellbeing and general health. “Compared to baseline, [Bacognize®] was associated with a 14% improvement in emotional wellbeing, 12% improvement in general health, and 16% reduction in pain (p<0.001). In contrast, the placebo [group] was associated with a 6% improvement in emotional wellbeing (p=0.007), 4% improvement in general health (p=0.039), and a non-significant 3% reduction in pain (p=0.474).”1
Kristen Marshall, digital marketing manager with Verdure Sciences, went on to explain, “this study, supports the opportunity to promote restful, restorative, and rejuvenating sleep with Bacognize®. It is a very relatable category / application to target; nearly everyone has wanted to wake up alert and refreshed, balance their circadian rhythm, but not want to feel groggy or tired when getting up. It pairs nicely with the study in medical students (Kumar et al, 2016) as improved learning has traditionally been associated with a good nights’ sleep, and just because you want to promote good quality sleep—restorative and restful—does not mean that you want to feel more tired when you lie down. Overall, we are thrilled with this new publication joining the growing body of evidence in support of Bacognize®.”
While health and wellbeing trends were invigorated by the onset of the global pandemic, these trends were inevitable and would have been seen over time. Trends within the industry may have some transient properties, but overall, it is predicted that this momentum will continue to persist.2 In particular, consumer demands are mirroring bigger conversations about mental wellbeing and healthy aging with heightened interest in innovative solutions associated with boosting health and wellbeing.2 Upticks in multi-prong support have also spurred innovation as consumers recognize the direct links between multiple areas of health, such as acknowledgement that mental and physical fatigue may lead to impaired immune health—if you are tired and rundown, you are more susceptible to opportunistic infection and illness.2 Consumers are adopting a proactive, long-term approach to health and wellness.2
Marshall summarized that these consumer trends are driving demand for ingredients supported by clinical research, quality, sustainability and traceability, clean labels, and robust adaptogenic offerings. “Bacognize is well poised to offer an adaptive approach to restorative health and is backed by traceability, clinical rigor, and quality assurance. This new publication only further exemplifies that traditional use with bacopa as modern applications with Bacognize® are well aligned with what consumers really want in a product for cognitive vitality, emotional and mental wellbeing, and now, restorative sleep.” †
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.Read more on Nutraceutical Business Review: Bacognize study demonstrates sleep and emotional benefits
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About Bacognize®: Bacognize® is a proprietary, clean label extract, derived from Bacopa monnieri, standardized to bioactive bacopa glycosides for adaptogenic cognitive wellness, memory, learning, focus, attention, mood stress management, emotional wellbeing, and promotes a balanced circadian rhythm for improved quality of life and restorative sleep. Bacopa has been used in Ayurveda for a multitude of purposes such as its nootropic effects promoting cognitive health. Clinical research suggests Bacognize® may offer robust cognitive, brain, and emotional wellbeing opportunities. Bacognize® is a registered trademark of Verdure Sciences®, Inc. To learn more about Bacognize, visit: vs-corp.com/bacognize
About Verdure Sciences®: Verdure Sciences supplies plant-based ingredients backed by science with an emphasis on sustainability, traceability, clean labels, global conscience, and stewardship. From growing and harvest to manufacturing, standardization, and research, our ingredient pipeline hold quality, integrity, efficacy, safety, and traceability as primary concerns in offering sustainable solutions for the global market. Verdure Sciences® is a registered trademark of Verdure Sciences®, Inc.
For our most current patent and trademark information, please visit: vs-corp.com/ip | Visit vs-corp.com for more information.
For a list of references, please visit: marketing.vs-corp.com/bacognize-science
1 – Lopresti AL et al. Effects of a Bacopa monnieri extract (Bacognize®) on stress, fatigue, quality of life and sleep in adults with self-reported poor sleep: A randomized, double-blind, placebo-controlled study. J Funct Foods. 2021 Aug 02. 85(2021): 104671. EPub 2021 Aug 5. doi: 10.1016/j.jff.2021.104671
2 – Hughes, Mike - head of research & insight. FMCG Gurus: What next for positive nutrition? Exploring consumer attitudes towards ingredients. FMCG Gurus presentation in A Naturally Informed Virtual Conference - Active Nutrition: Mastering the Market. Retrieved from presentation via live Zoom event on June 30, 2021. Slides available at: https://drive.google.com/file/d/1mtXH9BbuOwFr52a4wiL7KA5zTGQ-239v/view